The Best Hypoallergenic Sheets for 2020 | Ultimate Guide & Reviews

The right Hypoallergenic Sheets can help relieve your nighttime allergies while you sleep.

But with so many fabrics to choose from, you can be overwhelmed deciding on the perfect sheets for your allergies. And you definitely don’t want to waste your time with returns and exchanges.

That’s why we put together our Ultimate Guide to help you find the Best Hypoallergenic Sheets for 2020.

Here you will find everything you need to know to help make the right decision.

Which Type of Sheets are Best for My Allergies?

Depending on what allergies you suffer from, certain fabric types provide better relief than others.

For example, bamboo sheets are better at resisting dust-mites compared to cotton and microfiber.

However, for sensitive skin, 100% Organic Cotton is the best way to go! They may be a bit more expensive at first, but your skin will thank you for making the right decision.

Our Team-of-Experts put together this guide to make finding the right type of hypoallergenic bedding fast and simple.

You can use our Easy-to-Read Chart to compare their “Main Features”. Or you can skip to our Comprehensive Reviews for more details and information about each product.

We also have a section answering all the commonly asked questions about sheets to help with your allergies.


Hypoallergenic Sheets Comparison Chart

Below you will find our Easy-to-Read Comparison Chart of the Best Selling Allergy Sheets for 2020. We also included each of their Main Features and Benefits to help you make a quick comparison.

PhotoNameMain FeaturesLink
Pure Bamboo
100% Viscose Sheets
  • Best Overall!
  • Natural Bamboo Viscose
  • Dust Mite Resistant
  • Soft on Skin
Photos & ReviewCheck Price
Mellani
Hypoallergenic Sheets
  • Most Popular!
  • Over 88k Reviews
  • Brushed Microfiber
  • Lifetime Guarantee
Photos & ReviewCheck Price
Pure Parima Tan Giza Sheets IconPure Parima Yalda
100% Giza Cotton Sheets
  • Best for Sensitive Skin!
  • 100% Giza Cotton
  • OEKO-TEX Certified
  • Stays Soft for Years
Photos & ReviewCheck Price
Natemia
Organic Crib Sheets
  • Best Crib Sheets!
  • 100% Turkish Cotton
  • GOTS Certified
  • All-Around Elastic
Photos & ReviewCheck Price
Zen Bamboo
Bamboo Microfiber Sheets
  • Bamboo Rayon!
  • Bamboo/Microfiber Blend
  • Anti-Bacterial
  • Stain Resistant
Photos & ReviewCheck Price
Cosy House
Hypoallergenic Sheets
  • MicroFiber Blend!
  • 60% Bamboo 40% Microfiber
  • Wrinkle Resistant
  • 100% Money Back Guarantee
Photos & ReviewCheck Price
Sweet Home Collection
Allergen Sheets
  • Great Value!
  • 100% Brushed Microfiber
  • Deep Pockets
  • Over 40 Colors Available
Photos & ReviewCheck Price

Comprehensive Reviews

In the section below, you will find the following information about our featured Hypoallergenic Bed Sheets;

  • Detailed Descriptions
  • Actual Photos
  • List of Pros and Cons
  • Product Information
  • Product Availability

1. Pure Bamboo “Best Overall Sheets for Allergies”

Pure Bamboo HypoAllergenic Bamboo Viscose Sheets
Click to See on Amazon

First on our list are the bamboo sheets by “Pure Bamboo”. These sheets are made of 100% Natural Bamboo Viscose which is great for preventing dust-mites. Bamboo viscose is also Silky Smooth and Soft and won’t irritate dry skin or cause you to itch.

The company strives to provide quality bamboo bedding products with a 100% refund guarantee if you change your mind.

Skin sensitivity can be irritating if you are covered with stuffy bed sheets. However, pure bamboo sheets that prevent allergens are made to let vapor and moisture escape thereby ensuring the breath-ability of the body. This helps in keeping the body warm in cold weather and cool during warm weather conditions. Sheets with efficient breath-ability also ensure that the sheets remain fresh and odorless.

The hypoallergenic sheets are 16 inch deep pocketed, elastic and fit perfectly. The fitting makes the sleep remain peaceful since the bed sheet is held in place. A perfect fitting also makes the bedding look need and appealing. These bamboo sheets are more durable and softer than the cotton bed sheets. Every wash makes bamboo softer thereby increasing one’s comfort every time the sheets are washed. The double stitching is the contributing factor to the sheets’ durability.

Below you will find the available colors and sizes on Amazon

Available Sizes
  • Twin
  • Full
  • King
  • Queen
  • Cal King
  • Split King
Available Colors
  • Silver Pearl
  • Sea Glass
  • Cobalt Blue
  • Sterling Blue
  • Stone Grey
  • Ivory
  • Charcoal
  • Purple
  • Sand
  • White

The Pure Bamboo allergen-free bed sheets come in different sizes and colors. The available sizes are Twin, Full, Queen, King, California King, and Split King. A variety of colors and sizes ensures that all the customers’ tastes are provided. The available colors are silver pearl, ivory, charcoal, sea glass, purple, sand, cobalt blue, white, sterling blue and stone grey.

Pros
  • 100% Bamboo Viscose
  • Dust-Mite Resistant
  • Very Soft for Sensitive Skin
  • All-Around Elastic
  • Available in 10 different colors
Cons
  • Not available in Twin XL size

To conclude, Pure Bamboo sheets are the best bamboo sheets for people with sensitive skin, and want comfortably luxurious bedding.


2. Mellanni Sheets “Best Selling”

The next hypoallergenic sheets in our review are not only the most popular, but also the best selling sheets on Amazon. The Mellanni hypoallergenic bed sheet sets are 100% microfiber and ideal for any bedroom decor. If you haven’t tried Mellanni sheets, then you’re missing out on a great deal.

Hot Pink Mellanni Hypoallergenic Sheets Review
Click to See on Amazon

To start, the Mellanni Company produces different types of bedding to meet your need. Their microfiber sheets are soft and affordable for any budget. Their hypoallergenic bed sheets will provide you a comfortable and luxurious sleep.

Mellanni promises you high-quality sheets that are Durable and Built-to-Last. And provide a Lifetime Guarantee on their sheets. In case you’re not satisfied with the bed sheets, they will provide a full refund, no questions asked.

Mellanni makes its products with 100% and high quality microfiber. The look brought by these hypoallergenic sheets is the kind that you only see in advertisements and magazines. Who doesn’t want a fancy-looking bedroom?

If you’re looking to Surprise Family and Friends with these soft bed sheets as gifts. The marvelous look and softness, of the 1800 series, will make them smile their hearts out.

Mellanni uses a unique microfiber blend to make their sheets. Thus the sheets are Resistant to Fading, Wrinkles & Stains, and Dry Quickly after a cold machine wash.

Mellanni makes buying their sheets very easy. They provide many bright and vibrant colors to choose from. Another reason that makes them so easy to buy, is the wide range of sizes. No matter which size mattress you own, Mellanni has you covered!

The charts below show the different colors and sizes available on Amazon

Available Sizes
  • Twin
  • Full
  • King
  • Split King
  • Twin XL
  • Queen
  • Cal King
Available Colors
  • Hydrangea
  • Royal Blue
  • Burgundy
  • Olive Green
  • Purple
  • Emerald Green
  • Black
  • Brown
  • Blue
  • Grey
  • Gold
  • Tan
Pros
  • Over 50k Positive Reviews
  • 16-Inch Deep Pockets
  • All-Around Elastic
  • Resistant to Wrinkles, Fading & Static
  • Affordable, Comfortable & Luxurious
Cons
  • Difficult to wash by hand

To conclude, the Mellani 1800 sheets are great for repelling allergens, dust mites and moisture. The 50k+ Positive Reviews on Amazon has earned them the Top Spot on our list.


3. Pure Parima “Best Giza Sheets for Allergies”

Pure Parima Egyptian Cotton Sheets
Click to See on Pure Parima

If you’re looking for a more luxurious set of bed sheets that are hypoallergenic, Giza Sheets is the way to go.

Giza cotton has been used for centuries and is one of the most hypoallergenic fabrics available today.

Unlike traditional cotton fabrics, Giza cotton isn’t combined with other materials to improve their softness or durability. In-fact, Giza cotton sheets are known for becoming softer after each wash and age very well compared to other types of sheets.

The natural softness of 100% Pure Giza cotton won’t catch on dry skin or cause itchiness. It is also very easy to care for without the use of harsh chemicals or bleach.

Pure Parima uses a double-stitched hem for strength and durability. This added care ensures their sheets last for many more years compared to single hem stitching.

These sheets are exclusively available on Pure Parima’s website and can be delivered anywhere in the country within a few days.

Pros
  • 100% ELS Giza Cotton
  • Sustainable and Naturally Sourced
  • Breathable
  • Easy to Care for
  • Double Stitched Hem for Durability
Cons
  • Sold exclusively on their site

4. Natemia “Best Crib Sheets for Allergies”

Natemia Hypoallergenic Crib Sheets
Click to See on Natemia

For those looking for hypoallergenic crib sheets, you won’t find better than Organic Cotton! Going organic is a must when trying to avoid harsh chemicals and dyes that cause skin irritations.

The Natemia crib sheets are GOTS Certified, which means they are free from harmful chemicals, pesticides, and other toxic substances.

The Natemia Crib sheets are available in 2 different colors; White and Grey. They have an all-around elastic that prevents slipping as your toddler sleeps.

You can find them exclusively on Natemia.com and get Free 2-Day Shipping within the United States. To be sure you fall in love with their sheets, Natemia provides a 30-Night Sleep Trial with free return shipping.

Pros
  • 100% GOTS Certified Organic Cotton
  • Hypoallergenic
  • All-Around Elastic
  • 30-Night Sleep Trial
  • Free 2-Day Shipping
Cons
  • Only available in 2-pack
  • Only available in 2 colors

5. Zen Bamboo

Zen Bamboo Luxury 1500 Series Hypoallergenic Bed Sheets
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Zen Bamboo Luxury 1500 series is a set of hypoallergenic bed sheets that consists of 40% Rayon (a component of bamboo) and 60% brushed microfiber.

First of all, these allergen resistant sheets are by Zen Home Brands. They are located in the United States and commits itself to excellent customer satisfaction.

Zen Home Brands offers quality services to its customers. They offer a 30-day warranty to give customers enough time with the sheets to return them and get a full refund. All you have to do is get in touch with the company’s operatives. For other products and services, check out Zen Home Brands’ website.

The hypoallergenic bed sheets produced by Zen Bamboo are very comfortable and guarantee you a peaceful sleep all night. A relaxing sleep is every person’s dream, why not try out Zen Bamboo Luxury Hypoallergenic bedding? Zen Bamboo bed sheets are soft, stylish and lavish and cozy. Once washed (they are machine washable) they remain cool, fresh and dust free. Who doesn’t want a set of cooling bed sheets full of freshness and coziness?

These sheets prevent allergens and dust from interfering with your relaxing sleep. The blend of high quality bamboo and microfiber component ensures that the bed sheets remain durable and in good condition. They are a better choice compared to cotton sheets since they last longer. Zen Bamboo Luxury linens are resistant to numerous factors that may impede a peaceful night sleep. The sheets are resistant to fade, wrinkles, dust mites, stain, allergens, and a tedious task like ironing.

The charts below show the different colors and sizes available on Amazon

Available Sizes
  • Twin
  • Full
  • King
  • Queen
  • Cal King
Available Colors
  • White
  • Cream
  • Burgundy
  • Sky Blue
  • Purple
  • Navy Blue
  • Black
  • Brown
  • Olive
  • Grey
  • Gold
  • Taupe

The wide range of colors and sizes ensure that everyone’s interests are taken care of. The available size are Twin, Full, Queen, King and California King. The available colors will look fabulous on your bed. The colors are white, cream, sky blue, burgundy, gold, taupe, grey, brown, navy blue, olive, black, and purple.

Conclusion, Pros and Cons

In conclusion, the blend of 40% bamboo rayon and 60% microfiber ensures that your skin does not itch due to rough fabric. Zen Bamboo allergen-free bed sheets are the ideal bedding choice for you. Make sure you get yourself a set.

Pros
  • Wide range of colors available (12 colors)
  • Fits perfectly
  • Soft, cozy and luxurious
  • 100% quality guarantee
  • Durable
Cons
  • Not available in Twin XL and Split King sizes
  • Not deep pocketed

6. Cosy House Collection

Cosy House Collection Luxury Hypoallergenic Bamboo Sheets
Click to See on Amazon

Bed sheets are a common magnet for various allergens. These allergens include but are not limited to dust, dander or mites. Due to this high risk allergen factors it is necessary for one to pick a hypoallergenic bedding in order to stay infection free.

There are various kinds of bed sheets made of various materials from microfibers, cotton, silk, organic cotton, to bamboo fibers. In the search for comfort at night after a long day, one needs to have the best bed sheet quality that enable a smooth relaxing sleep, is free from allergies and discomforts like hotness.

Quite often, most people are torn between various brands as the market is flooded with various brands of varying qualities. However, Cosy House Collection Luxury Bamboo Bed Sheet Set remains the best ahead of the rest.

These allergy free bedding are made of materials that aid in keeping allergens away. Cosy house is a leading dealer in bed sheets that are hypoallergenic and comfort friendly. Other than bed sheets, they also deal in hypoallergenic pillows, comforters, rugs and mats. Made of natural bamboo fibers, hypoallergenic bedding also known as allergy free bed sheets is made of rayon.

Rayon is a chemical that is blended with the natural bamboo fibers to create desired end product, this chemical however can be a skin irritant to people with sensitive skin.

Hypoallergenic sheets are made of ultra thin fibers. These fibers hen sewn together ensure compactness in the sheets, this compactness helps with the prevention of the spread of allergens once released when one is sleeping. The tightness prevents the sieving of allergens through the bedding.

The charts below show the different colors and sizes available on Amazon

Available Sizes
  • Twin
  • Twin XL
  • Full
  • King
  • Queen
  • Cal King
  • Split King
Available Colors
  • Turquoise
  • Sage Green
  • Purple
  • Black
  • White
  • Pink

This bedding comes in a 4- piece set, two pillow cases, one oversize sheet and a flat sheet. The sizes include, Twin, Twin XL, Full, King, Queen, California King and Split King. These allergen prevention sheets also come in different colors; black, turquoise, sage green, purple, black, white, and pink.

Conclusion, Pros and Cons

Although there are cons to the use of natural bamboo hypoallergenic fibers, the pros outweigh them. This makes these sheets the best from anyone seeking value for their money and a relaxing sleep free from allergens.

Pros
  • Allergen free hence promoting healthy living
  • Luxurious feel thus considered most comfortable
  • They come in a various sizes
  • Long lasting
  • Produced in ten different colors
Cons
  • They are expensive.
  • Similar sets are made of lesser quality fibers that jeopardize its benefits.

7. 1500 Supreme Collection

1500 Supreme Collection Extra Soft Luxury Hypoallergenic Bed Sheets
Click to See on Amazon

Without a doubt, when shopping for bedding particularly bed sheets there are several different materials that one will come across. Currently sheets made of microfibers are the most popular.

Compared to the Egyptian cotton, the 1500 supreme has an edge on softness. These sheets contain a major feature from the manufacturer. They are considered as deep pocket sheets because they stretch over mattresses as thick as fourteen inches thick. These sheets are made of cotton, flannel or sateen just like any other bed sheets.

They are also considered as hypoallergenic sheets because they are allergen transmission resistant. This resistance is because of the microfibers use to make these sheet which increase a high thread count on the sheets. These microfibers when sewn together enhance compactness that prevents allergens like dust from further spreading on the bedding.

The better stitching done to these deep pocket allergen free sheets and stronger weaving has made them a number one choice compared to other similar sheets in the market.

The microfibers not only promote hypoallergenic nature but also improve the resistance of the 1500 supreme collection sheets to shrinking and wrinkling. This satisfies the market demands as people are looking for sheets that are easy to wash and dry without a creased line in them.

These sheets are 100% microfiber, and come in a four piece set which is inclusive of a pillowcases, deep pocket fitted sheets. This bedding is machine was friendly, does not require bleaching nor ironing since its wrinkle free.

The charts below show the different colors and sizes available on Amazon

Available Sizes
  • Twin
  • Twin XL
  • Full
  • King
  • Queen
  • Queen RV
  • Cal King
  • Split King
Over 40 Colors Available
  • Checkered
  • Paisley
  • Block Colors
  • Patterns

These deep pocket wrinkle free and allergen free sheets come in a variety of sizes and colors. The sizes are Twin, Twin XL, Full, Queen, RV Queen, King, California King and Split King. The colors are over 40, some are block colors, and others checkered, paisley and pattern.

Conclusion, Pros and Cons

The pros outweigh the cons of these sheets these make them worth ones dimes. It is also friendly to people with allergies to allergens such as dust and dander, but, it all comes down to what one is looking for in a sheet, it is a question of choice and preferences.

Pros
  • Wrinkle free thus they do not require ironing
  • Deep pocketed thus making then able to fit over thick mattresses
  • Soft and luxurious
  • Easy to dry after washing.
  • Durable
Cons
  • Some sheets tend to fade and shrink with time as they are washed.
  • Low quality sheets rip too easily due to the low quality fiber used.

Hypoallergenic Sheets Comprehensive Buyer’s Guide

The health benefits of hypoallergenic bed sheets are Nothing to Sneeze At!

Okay, bad pun aside, hypoallergenic sheets can contribute to your health in ways you may never have ever expected. Hypoallergenic Sure, they cut down on allergens, hence their name. But the things they help keep at bay is nothing short of miraculous. And when you consider that you’ll spend over a third of your life in bed—that’s 25 full years in the land of nod– it makes sense to have something comfortable, durable, and safe to curl up with.

First things first: Allergens. You’ve heard of them. They are the things that make your nose water, then they clog it, then they send you into sneezing fits. Horrible things, these allergens. But what exactly are they?

Well, in the bedroom, there is a microscopic cocktail of cooties that make your bed unhealthy and uncomfortable. The chief sneeze ingredients are mold spores, dust mites, pollen, dead skin, and animal dander. Yes, some dogs like shih tzus and snicker-doodles are hypoallergenic, but it’s more likely that your family dog is bringing the funk and the allergens into your bed. The solution is simple, comfortable and surprisingly affordable: Hypoallergenic sheets.


Best Thread Count for Hypoallergenic Sheets

Most producers of sheets concede that a 200-thread count is perfectly acceptable and soothing to the touch. 400 thread count is really top of the range, giving an exquisite touch and feel for your weary bones at the end of the day. But anything above that, 800, 1000, 1200….well, that’s marketing, so don’t be fooled.

Plus, thread counts go out the window when discussing microfiber hypoallergenic sheets.

Take bamboo. Yes, bamboo. It doesn’t seem like the obvious choice to create strong yet exceptionally smooth sheets that are as comfortable as they are hypoallergenic. But it’s true. Bamboo is an excellent fiber source with a thicker and longer thread than cotton.  This allows it to expand in hot weather—allowing it to breathe better than cotton. In the colder months, it does the reverse.

Bamboo thread contracts, helping you retain your body heat and stave of winter’s chill. One last thing about bamboo sheets, they are an excellent example of how microfiber sheets can be thin by comparison to wool or cotton, but much more durable.

Hypoallergenic sheets aren’t limited to bamboo.  Polyester and Rayon are dream makers when it comes to microfiber. Gone are the days when synthetics were deemed a poor substitute for natural fibers. Many people like the fact that these microfibers are virtually hassle free. They don’t shrink or pill. They don’t fade. And thanks to manufacturing advancements, they breathe like cotton so you’ll wake refreshed and ready for the day ahead. That is, if you can force yourself to leave the comfort of your snuggly and allergen-free bed.


Other Hypoallergenic Bedding to Consider

Hypoallergenic sheets are just the icing on the cake, or bed. But don’t stop there. Your entire body is immersed in your bed for eight hours a day, so treat yourself to some hypoallergenic love from head toe.  Consider adding a hypoallergenic mattress cover to give your bed a fantastic, allergy-fighting foundation night after night. And that about your dream-maker? Surely your head deserves to be cradled in hypoallergenic bliss, too.

A synthetic pillow made with memory foam and polyester can fit off allergen thanks to their antimicrobial properties—something that traditional down-filled pillows do not possess. In fact, down pillows could very well be adding allergens to your bedroom! Talk about a nightmare.

The newest wave of hypoallergenic materials delivers a healthier option without sacrificing comfort. Speaking of comforters, there’s no better way to top off your bed than with a comforter made from silk, wool, organic cotton, or microfiber materials like rayon and polyester. Here, thread count does matter. Going to 400 will ensure a tighter weave creating a more impenetrable defense against those pesky mites and other allergens.


Frequently Asked Questions

What is the best mattress for allergy sufferers?

Memory foam and latex mattresses give you the best defense against allergens. Giant strides have been made in creating breathable tops to reduce overheating while deliver superior comfort.  Watch out for Hybrid mattresses—that have spring coil and foam. They can actually exacerbate allergies as they invite mold and mildew to grow inside.

Are hypoallergenic sheets worth it?

With hypoallergenic sheets, you might think that this sort of luxury is out of reach. Think again. Both cotton and microfiber hypoallergenic sheets can be are plentiful and as low as $30 a set. So, you can sleep like a queen in your king–or a king in your queen–without having to pay king’s ransom.

Is Egyptian cotton hypoallergenic?

Yes. Egyptian cotton – like all organic cotton and silk – lend a mighty hand in resisting potentially allergy-inducing causes like dust mites and mold.

What’s the best pillow for allergies?

Wool and cotton provide fantastic allergy-reducing features due to their natural construction. Latex pillows can also be used to great effect in warding off dust mites while offering breathability.

Does lack of sleep make my allergies worse?

Lack of sleep while sleeping on a bed full with allergens can create a vicious cycle. It might make sense to replace your pillow, sheets, and mattress cover with hypoallergenic upgrades. This can give you a better chance of a good night’s sleep. This in turn, reduces stress, which can make you less sensitive to allergens in and outside of the home.

Do hypoallergenic sheets really help with allergies?

In a word, YES!  In fact, hypoallergenic sheets have been around longer than the term hypoallergenic itself. Wool and organic cotton are naturally hypoallergenic. Thanks to their breathability, sheets made from these natural materials breathe better and dry out allergens, especially dust mites. Cotton has long been the gold standard when it comes to comfort on a well-appointed bed. Savvy buyers already know that the higher the thread count, the softer and more luxurious cotton sheets tend to be.  To a point.


Conclusion

Rest assured that hypoallergenic sheets – and other bedding – really do work. Hypoallergenic bed sheets are super comfy. They resist creepy bed allergens that can create nightmares, literally and figuratively. And, they’re as affordable as regular sheets.

What are you waiting for? Trade in your old sheets for the dream-inducing, sneeze-reducing hypoallergenic sheets and wake up on the right side of the bed day after day after day.